ABSTRACT
Objective To evaluate the anti-dysmenorrhea efficacy of habitat fresh-cut processed and traditional processed Linderae Radix based on the dysmenorrhea model. Methods By using the estrogen-induced dysmenorrhea model of ICR mice, the effect of treatment from two different processing methods on dysmenorrhea was compared by recording the writhing reaction as well as the changes of levels of prostaglandin E2 (PGE2), prostaglandin F2α (PGF2α), vasopressin (AVP), and β-endorphin (β-EP). Results Compared with the model group, Linderae Radix from two different processing methods significantly reduced the frequency of writhing (P 0.05). Conclusion The two processing methods of Linderae Radix both have good therapeutic effect on dysmenorrhea model mice, and the effect of habitat processed Linderae Radix is not inferior to that of traditional processed Linderae Radix.
ABSTRACT
AIM To evaluate the quality of Linderae Radix from different growing areas.METHODS Hot dipping method was applied to determining the extract content.HPLC was adopted in the content derermination of linderane,linderalactone and norisoboldine.Then SPSS19.0 software was used for principal component analysis.RESULTS The effect degrees of various index components were in sequence of extract ＞ norisoboldine ＞ linderalactone ＞ linderane.The accumulative contribution rate of the first two principal components (total content of four index components,extract content) reached 86.86％.The comprehensive score of Linderae Radix from Taizhou (Zhejiang) was the highest.CONCLUSION Taking Taizhou (Zhejiang) as the genuine producing area of Linderae Radix has a certain scientific basis.
ABSTRACT
AIM To evaluate the quality of Linderae Radix from different growing areas.METHODS Hot dipping method was applied to determining the extract content.HPLC was adopted in the content derermination of linderane,linderalactone and norisoboldine.Then SPSS19.0 software was used for principal component analysis.RESULTS The effect degrees of various index components were in sequence of extract ＞ norisoboldine ＞ linderalactone ＞ linderane.The accumulative contribution rate of the first two principal components (total content of four index components,extract content) reached 86.86％.The comprehensive score of Linderae Radix from Taizhou (Zhejiang) was the highest.CONCLUSION Taking Taizhou (Zhejiang) as the genuine producing area of Linderae Radix has a certain scientific basis.